Tag Archives: NMD

Re-opening the discussion on mRNA decay inside P-bodies

Processing bodies (P-bodies, PBs) are aggregates of mRNA degradation proteins, suggested 20 years ago to be sites of mRNA degradation. Later work provided evidence to the contrary, and the function of PBs remained controversial. A new pre-print from Bin Wu’s lab brings us back to this debate, with new evidence for a role in degradation. Bonus – how phototoxicity affects the outcome. (Note – updated with published paper).

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